Incorporating computed tomography (CT) reconstruction operators into differentiable pipelines has proven beneficial in many applications. Such approaches usually focus on the projection data and keep the acquisition geometry fixed. However, precise knowledge of the acquisition geometry is essential for high quality reconstruction results. In this paper, the differentiable formulation of fan-beam CT reconstruction is extended to the acquisition geometry. This allows to propagate gradient information from a loss function on the reconstructed image into the geometry parameters. As a proof-of-concept experiment, this idea is applied to rigid motion compensation. The cost function is parameterized by a trained neural network which regresses an image quality metric from the motion affected reconstruction alone. Using the proposed method, we are the first to optimize such an autofocus-inspired algorithm based on analytical gradients. The algorithm achieves a reduction in MSE by 35.5 % and an improvement in SSIM by 12.6 % over the motion affected reconstruction. Next to motion compensation, we see further use cases of our differentiable method for scanner calibration or hybrid techniques employing deep models.

替代模型用于减轻工程任务中的计算负担，这些计算负担需要重复评估计算要求的物理系统模型，例如不确定性的有效传播。对于显示出非常非线性依赖其输入参数的模型，标准的替代技术（例如多项式混沌膨胀）不足以获得原始模型响应的准确表示。通过应用有理近似，对于通过有理函数准确描述的模型可以有效地降低近似误差。具体而言，我们的目标是近似复杂值模型。获得替代系数的一种常见方法是最小化模型和替代物之间的基于样本的误差，从最小二乘意义上讲。为了获得原始模型的准确表示并避免过度拟合，样品集的量是扩展中多项式项数的两到三倍。对于需要高多项式程度或在其输入参数方面具有高维度的模型，该数字通常超过负担得起的计算成本。为了克服这个问题，我们将稀疏的贝叶斯学习方法应用于理性近似。通过特定的先前分布结构，在替代模型的系数中诱导稀疏性。分母的多项式系数以及问题的超参数是通过类型-II-Maximim-Maximim类似方法来确定的。我们应用了准牛顿梯度散发算法，以找到最佳的分母系数，并通过应用$ \ mathbb {cr} $ -Colculus来得出所需的梯度。

We address the challenge of building domain-specific knowledge models for industrial use cases, where labelled data and taxonomic information is initially scarce. Our focus is on inductive link prediction models as a basis for practical tools that support knowledge engineers with exploring text collections and discovering and linking new (so-called open-world) entities to the knowledge graph. We argue that - though neural approaches to text mining have yielded impressive results in the past years - current benchmarks do not reflect the typical challenges encountered in the industrial wild properly. Therefore, our first contribution is an open benchmark coined IRT2 (inductive reasoning with text) that (1) covers knowledge graphs of varying sizes (including very small ones), (2) comes with incidental, low-quality text mentions, and (3) includes not only triple completion but also ranking, which is relevant for supporting experts with discovery tasks. We investigate two neural models for inductive link prediction, one based on end-to-end learning and one that learns from the knowledge graph and text data in separate steps. These models compete with a strong bag-of-words baseline. The results show a significant advance in performance for the neural approaches as soon as the available graph data decreases for linking. For ranking, the results are promising, and the neural approaches outperform the sparse retriever by a wide margin.

Machine learning models are typically evaluated by computing similarity with reference annotations and trained by maximizing similarity with such. Especially in the bio-medical domain, annotations are subjective and suffer from low inter- and intra-rater reliability. Since annotations only reflect the annotation entity's interpretation of the real world, this can lead to sub-optimal predictions even though the model achieves high similarity scores. Here, the theoretical concept of Peak Ground Truth (PGT) is introduced. PGT marks the point beyond which an increase in similarity with the reference annotation stops translating to better Real World Model Performance (RWMP). Additionally, a quantitative technique to approximate PGT by computing inter- and intra-rater reliability is proposed. Finally, three categories of PGT-aware strategies to evaluate and improve model performance are reviewed.

Efficient surrogate modelling is a key requirement for uncertainty quantification in data-driven scenarios. In this work, a novel approach of using Sparse Random Features for surrogate modelling in combination with self-supervised dimensionality reduction is described. The method is compared to other methods on synthetic and real data obtained from crashworthiness analyses. The results show a superiority of the here described approach over state of the art surrogate modelling techniques, Polynomial Chaos Expansions and Neural Networks.

This short report reviews the current state of the research and methodology on theoretical and practical aspects of Artificial Neural Networks (ANN). It was prepared to gather state-of-the-art knowledge needed to construct complex, hypercomplex and fuzzy neural networks. The report reflects the individual interests of the authors and, by now means, cannot be treated as a comprehensive review of the ANN discipline. Considering the fast development of this field, it is currently impossible to do a detailed review of a considerable number of pages. The report is an outcome of the Project 'The Strategic Research Partnership for the mathematical aspects of complex, hypercomplex and fuzzy neural networks' meeting at the University of Warmia and Mazury in Olsztyn, Poland, organized in September 2022.

In recent years distributional reinforcement learning has produced many state of the art results. Increasingly sample efficient Distributional algorithms for the discrete action domain have been developed over time that vary primarily in the way they parameterize their approximations of value distributions, and how they quantify the differences between those distributions. In this work we transfer three of the most well-known and successful of those algorithms (QR-DQN, IQN and FQF) to the continuous action domain by extending two powerful actor-critic algorithms (TD3 and SAC) with distributional critics. We investigate whether the relative performance of the methods for the discrete action space translates to the continuous case. To that end we compare them empirically on the pybullet implementations of a set of continuous control tasks. Our results indicate qualitative invariance regarding the number and placement of distributional atoms in the deterministic, continuous action setting.

Artificial Intelligence (AI) has become commonplace to solve routine everyday tasks. Because of the exponential growth in medical imaging data volume and complexity, the workload on radiologists is steadily increasing. We project that the gap between the number of imaging exams and the number of expert radiologist readers required to cover this increase will continue to expand, consequently introducing a demand for AI-based tools that improve the efficiency with which radiologists can comfortably interpret these exams. AI has been shown to improve efficiency in medical-image generation, processing, and interpretation, and a variety of such AI models have been developed across research labs worldwide. However, very few of these, if any, find their way into routine clinical use, a discrepancy that reflects the divide between AI research and successful AI translation. To address the barrier to clinical deployment, we have formed MONAI Consortium, an open-source community which is building standards for AI deployment in healthcare institutions, and developing tools and infrastructure to facilitate their implementation. This report represents several years of weekly discussions and hands-on problem solving experience by groups of industry experts and clinicians in the MONAI Consortium. We identify barriers between AI-model development in research labs and subsequent clinical deployment and propose solutions. Our report provides guidance on processes which take an imaging AI model from development to clinical implementation in a healthcare institution. We discuss various AI integration points in a clinical Radiology workflow. We also present a taxonomy of Radiology AI use-cases. Through this report, we intend to educate the stakeholders in healthcare and AI (AI researchers, radiologists, imaging informaticists, and regulators) about cross-disciplinary challenges and possible solutions.

Understanding our brain is one of the most daunting tasks, one we cannot expect to complete without the use of technology. MindBigData aims to provide a comprehensive and updated dataset of brain signals related to a diverse set of human activities so it can inspire the use of machine learning algorithms as a benchmark of 'decoding' performance from raw brain activities into its corresponding (labels) mental (or physical) tasks. Using commercial of the self, EEG devices or custom ones built by us to explore the limits of the technology. We describe the data collection procedures for each of the sub datasets and with every headset used to capture them. Also, we report possible applications in the field of Brain Computer Interfaces or BCI that could impact the life of billions, in almost every sector like healthcare game changing use cases, industry or entertainment to name a few, at the end why not directly using our brains to 'disintermediate' senses, as the final HCI (Human-Computer Interaction) device? simply what we call the journey from Type to Touch to Talk to Think.

Modern mobile burst photography pipelines capture and merge a short sequence of frames to recover an enhanced image, but often disregard the 3D nature of the scene they capture, treating pixel motion between images as a 2D aggregation problem. We show that in a "long-burst", forty-two 12-megapixel RAW frames captured in a two-second sequence, there is enough parallax information from natural hand tremor alone to recover high-quality scene depth. To this end, we devise a test-time optimization approach that fits a neural RGB-D representation to long-burst data and simultaneously estimates scene depth and camera motion. Our plane plus depth model is trained end-to-end, and performs coarse-to-fine refinement by controlling which multi-resolution volume features the network has access to at what time during training. We validate the method experimentally, and demonstrate geometrically accurate depth reconstructions with no additional hardware or separate data pre-processing and pose-estimation steps.